Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 14/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401796 | 0.89 | BDKRB1 (0.67) | BDKRB1ALDH1A1POLBGAA | |
| SCHEMBL6403863 | 0.89 | BDKRB1 (0.67) | BDKRB1ALDH1A1POLBGAA | |
| SCHEMBL5801007 | 0.87 | BDKRB1 (0.68) | BDKRB1ALDH1A1POLBGAA | |
| SCHEMBL5797997 | 0.87 | BDKRB1 (0.65) | BDKRB1ALDH1A1POLBGAA | |
| SCHEMBL6402861 | 0.86 | BDKRB1 (0.79) | BDKRB1ALDH1A1POLB | |
| SCHEMBL645808 | 0.86 | BDKRB1 (0.79) | BDKRB1ALDH1A1POLB | |
| SCHEMBL5797894 | 0.86 | BDKRB1 (0.64) | BDKRB1ALDH1A1POLB | |
| SCHEMBL645871 | 0.82 | BDKRB1 (0.73) | BDKRB1ALDH1A1POLBGAA | |
| SCHEMBL5797511 | 0.82 | BDKRB1 (0.60) | BDKRB1ALDH1A1POLB | |
| SCHEMBL4425827 | 0.79 | BDKRB1 (0.77) | BDKRB1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572209-A4 | NOVEL QUINOXALINONE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS | MERCK & CO INC (US) | 2006-12-06 | — | — | EP | disclosed |
| EP-1572209-A1 | NOVEL QUINOXALINONE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS | Merck & Co., Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054584-A1 | NOVEL QUINOXALINONE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS | MERCK & CO., INC. (US) | 2004-07-01 | — | — | WO | disclosed |