Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.63 |
| ▸ | FNTB | P49356 | 17/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499970 | 0.94 | FNTA (0.71) | FNTAFNTB | |
| SCHEMBL3500284 | 0.91 | FNTA (0.63) | FNTAFNTB | |
| SCHEMBL3503061 | 0.91 | FNTA (0.63) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3500586 | 0.90 | FNTA (0.73) | FNTAFNTBALDH1A1LMNA | |
| SCHEMBL3499547 | 0.90 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL3502056 | 0.89 | FNTA (0.65) | FNTAFNTBALDH1A1LMNA | |
| SCHEMBL3500156 | 0.87 | FNTA (0.61) | FNTAFNTBALDH1A1LMNA | |
| SCHEMBL3502480 | 0.87 | FNTA (0.58) | FNTAFNTBALDH1A1LMNA | |
| SCHEMBL3501377 | 0.86 | FNTA (0.57) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3501815 | 0.86 | FNTA (0.65) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005089515-A9 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | BRIGHAM & WOMENS HOSPITAL (US) | 2006-01-26 | — | — | WO | disclosed |