Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316433 | 0.82 | TLR8 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL4317813 | 0.81 | TLR8 (0.38) | TLR7TLR8NUDT1 | |
| SCHEMBL5823019 | 0.79 | TLR8 (0.36) | TLR7TLR8NUDT1 | |
| SCHEMBL5355397 | 0.78 | TLR8 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL3866877 | 0.75 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL29374514 | 0.74 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL4753517 | 0.74 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL5823013 | 0.73 | TLR8 (0.36) | TLR7TLR8NUDT1 | |
| SCHEMBL4315451 | 0.73 | TLR8 (0.36) | TLR7TLR8NUDT1 | |
| SCHEMBL3862298 | 0.72 | TLR7 (0.51) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699788-A2 | IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES | 3M Innovative Properties Company (US) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066169-A2 | IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL, AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |