Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL2392562 | 0.92 | TSHR (0.51) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL7058394 | 0.83 | TSHR (0.38) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL14681170 | 0.81 | TSHR (0.47) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL11498319 | 0.80 | TSHR (0.43) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL9579858 | 0.80 | TSHR (0.40) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| Phosphoric Acid SCHEMBL27674703 | 0.80 | TSHR (0.55) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL3199632 | 0.78 | CYP3A4 (0.39) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL11239793 | 0.78 | TSHR (0.44) | TSHRPKMSMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL9550690 | 0.77 | MEN1 (0.40) | TSHRTDP1HPGDMEN1LMNA | |
| SCHEMBL11417724 | 0.75 | TDP1 (0.39) | TSHRPKMSMN1; SMN2CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447355-A | Preparation method of milbelin intermediate | 南京威凯尔生物医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| EP-1669353-A1 | Process for preparing alpha, beta - unsaturated ester | DAISO CO., LTD. (JP) | 2006-06-14 | — | — | EP | claimed |
| EP-0260162-B1 | BICYCLIC AROMATIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA Groupement d'Intérêt Economique dit: (FR) | 1990-11-14 | — | — | EP | claimed |
| US-4892940-A | Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions | L'OREAL (FR) | 1990-01-09 | — | — | US | claimed |
| US-4833240-A | SKIN DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLLERGENS; ANTITUMOR AGENTS; OPHTHALMOLOGY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1989-05-23 | — | — | US | claimed |
| JP-63243092-A | — | — | None | — | — | JP | disclosed |
| JP-63233991-A | — | — | None | — | — | JP | disclosed |
| JP-63233990-A | — | — | None | — | — | JP | disclosed |
| EP-4400584-A2 | GUIDE RNA WITH CHEMICAL MODIFICATIONS | Agilent Technologies, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| EP-3227447-B1 | GUIDE RNA WITH CHEMICAL MODIFICATIONS | AGILENT TECHNOLOGIES INC (US) | 2024-04-24 | — | — | EP | disclosed |
| CN-117447355-B | Preparation method of milbelin intermediate | 南京威凯尔生物医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117447355-A | Preparation method of milbelin intermediate | 南京威凯尔生物医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |
| US-4892940-A | Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions | L'OREAL (FR) | 1990-01-09 | — | — | US | disclosed |
| US-4833240-A | SKIN DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLLERGENS; ANTITUMOR AGENTS; OPHTHALMOLOGY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1989-05-23 | — | — | US | disclosed |
| US-4829080-A | SKIN DISORDERS, PSORIASIS, ACNE | L'OREAL (FR) | 1989-05-09 | — | — | US | disclosed |
| JP-S63243092-A | PHOSPHONOACETATE DERIVATIVE AND PRODUCTION THEREOF | HODOGAYA CHEM CO LTD | 1988-10-07 | — | — | JP | disclosed |
| JP-S63233990-A | PRODUCTION OF PHOSPHONOACETATE DERIVATIVE | HODOGAYA CHEM CO LTD | 1988-09-29 | — | — | JP | disclosed |
| JP-S63233991-A | PRODUCTION OF PHOSPHONOACETAMIDE DERIVATIVE | HODOGAYA CHEM CO LTD | 1988-09-29 | — | — | JP | disclosed |
| US-4124588-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-11-07 | — | — | US | disclosed |