Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528658 | 0.78 | KDM4E (0.42) | KDM4EGPR3HPGDHSD17B10USP5 | |
| SCHEMBL204996 | 0.78 | KDM4E (0.42) | KDM4EGPR3HPGDHSD17B10ERN1 | |
| SCHEMBL5092806 | 0.78 | KDM4E (0.42) | KDM4EGPR3HPGDHSD17B10ERN1 | |
| SCHEMBL4703998 | 0.78 | KDM4E (0.42) | KDM4EGPR3HPGDHSD17B10ERN1 | |
| SCHEMBL1486425 | 0.76 | KDM4E (0.41) | KDM4EGPR3HPGDHSD17B10ERN1 | |
| SCHEMBL2252071 | 0.75 | FGFR1 (0.54) | RAB9AADORA3 | |
| SCHEMBL2707327 | 0.74 | KDM4E (0.39) | KDM4EGPR3HPGDHSD17B10NPC1 | |
| SCHEMBL8721713 | 0.74 | KDM4E (0.39) | KDM4EGPR3HPGDHSD17B10RAB9A | |
| SCHEMBL4817117 | 0.74 | KDM4E (0.39) | KDM4EGPR3HPGDHSD17B10RAB9A | |
| SCHEMBL9601955 | 0.74 | SMN1; SMN2 (0.42) | KDM4EGPR3RAB9ANPC1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |