Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDKN1A | P38936 | 1/20 | 0.72 |
| ▸ | BRAF | P15056 | 14/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808313 | 0.91 | CDKN1A (0.88) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5807610 | 0.90 | CDKN1A (0.68) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5812342 | 0.85 | CDKN1A (0.68) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5823272 | 0.84 | CDKN1A (1.00) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5800105 | 0.83 | CDKN1A (0.65) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5820313 | 0.83 | CDKN1A (0.93) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5822354 | 0.83 | CDKN1A (0.93) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5814680 | 0.83 | CDKN1A (0.86) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5821207 | 0.82 | CDKN1A (0.92) | CDKN1ABRAFMAPK13PIM1 | |
| SCHEMBL5808580 | 0.82 | CDKN1A (0.92) | CDKN1ABRAFMAPK13PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033795-A2 | SUBSTITUTED PYRAZOLO [1, 5-A] PYRIMIDINES FOR INHIBITING ABNORMAL CELL GROWTH | WYETH (US) | 2006-03-30 | — | — | WO | claimed |