Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290334 | 0.87 | PARP1 (0.60) | PARP1RXFP1PRMT5 | |
| SCHEMBL29698487 | 0.83 | PARP1 (0.64) | PARP1RXFP1PRMT5 | |
| SCHEMBL5480367 | 0.81 | PARP1 (0.66) | PARP1RXFP1PRMT5 | |
| SCHEMBL1477698 | 0.80 | PARP1 (0.69) | PARP1RXFP1PRMT5 | |
| SCHEMBL24754417 | 0.79 | PARP1 (0.59) | PARP1RXFP1PRMT5 | |
| SCHEMBL26177802 | 0.79 | PARP1 (0.59) | PARP1RXFP1PRMT5 | |
| SCHEMBL112629 | 0.78 | PARP1 (0.70) | PARP1RXFP1 | |
| SCHEMBL536589 | 0.77 | PARP1 (0.64) | PARP1 | |
| SCHEMBL5823499 | 0.77 | MAPT (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL2127143 | 0.76 | PARP1 (0.55) | PARP1RXFP1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130673-A1 | 3-BENZOIMIDAZOLYL-PYRAZOLOPYRIDINES USEFUL IN TREATING KINASE DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-12-07 | — | — | WO | claimed |