Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155960 | 0.82 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL5823792 | 0.80 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL1490971 | 0.78 | TLR7 (0.63) | TLR7TLR8NUDT1 | |
| SCHEMBL3865770 | 0.76 | TLR7 (0.78) | TLR7TLR8NUDT1 | |
| SCHEMBL29977522 | 0.75 | TLR7 (0.74) | TLR7TLR8NUDT1ADORA2A | |
| SCHEMBL893024 | 0.75 | TLR7 (0.74) | TLR7TLR8NUDT1ADORA2A | |
| SCHEMBL4393435 | 0.75 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| SCHEMBL3864304 | 0.73 | TLR7 (0.56) | TLR7TLR8NUDT1 | |
| SCHEMBL1486429 | 0.72 | TLR7 (0.79) | TLR7TLR8NUDT1 | |
| SCHEMBL1490440 | 0.72 | TLR7 (0.58) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038923-A2 | ARYL SUBSTITUTED IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |