SCHEMBL5823804

SCHEMBL5823804

CN(C(=O)O)[C@@H]1CN(c2ccc(N3CCN(c4ccc([N+](=O)[O-])s4)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.44
MAOA P21397 3/20 0.44
LMNA P02545 1/20 0.43
PTGS1 P23219 1/20 0.43
CALML3 P27482 1/20 0.43
SDHA P31040 1/20 0.43
F10 P00742 12/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5799933 0.84 MAOB (0.46) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5822532 0.84 MAOB (0.45) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5808176 0.83 MAOB (0.51) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5799311 0.83 MAOB (0.59) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5822534 0.82 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5799930 0.82 MAOB (0.43) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6506664 0.82 F10 (0.54) MAOBMAOALMNAPTGS1CALML3
SCHEMBL27614703 0.82 MAOB (0.55) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5813447 0.81 MAOB (0.51) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5813450 0.81 MAOB (0.51) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006043121-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-27 WO disclosed