Oxyquinoline

Oxyquinoline

SCHEMBL5824010

Oc1cccc2cccnc12.c1ccc2ncccc2c1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.78
MMP2 P08253 2/20 0.78
CHRM1 P11229 1/20 0.78
COMT P21964 1/20 0.78
ADRA1A P35348 1/20 0.78
METAP2 P50579 1/20 0.78
METAP1 P53582 1/20 0.78
HDAC8 Q9BY41 1/20 0.78
KDM4E B2RXH2 7/20 0.66
ALOX12 P18054 3/20 0.66
ALDH1A1 P00352 5/20 0.63
LMNA P02545 4/20 0.61
KMT2A Q03164 6/20 0.50
MAPT P10636 4/20 0.50
GAA P10253 3/20 0.50
RAB9A P51151 2/20 0.50
ACHE P22303 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MEN1 O00255 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL28221369 0.98 TSHR (0.75) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL15388367 0.98 TSHR (0.75) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL27430306 0.98 TSHR (0.75) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL27844005 0.98 TSHR (0.75) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL28286063 0.92 TSHR (0.66) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL27626787 0.92 KDM4E (0.81) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL28240474 0.92 TSHR (0.66) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL28849328 0.89 KDM4E (0.67) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL12492889 0.88 TSHR (0.91) TSHRMMP2CHRM1COMTADRA1A
Oxyquinoline SCHEMBL29716519 0.88 TSHR (1.00) TSHRMMP2CHRM1COMTADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146201-A Novel preparation method of tergolian prazan 开封明仁药业有限公司 2024-06-07 CN claimed
CN-110396116-A Ketone-imidazoline -2- imine ligand [N, O] bidentate nickel, palladium complex and the preparation method and application thereof UNIV NATIONAL DONG HWA 2019-11-01 CN claimed
CN-107710442-B Organic electroluminescent device 国立大学法人九州大学 2019-09-17 CN claimed
CN-110240907-A Etching solution for selectively removing silicon-germanium alloy from silicon-germanium/germanium stack during semiconductor device fabrication 弗萨姆材料美国有限责任公司 2019-09-17 CN claimed
CN-110105278-A A kind of pyrene azo 8-hydroxyquinoline fluorescent material and its preparation method and application 莆田学院 2019-08-09 CN claimed
CN-110052230-A A kind of self-repairing microcapsule and its preparation method and application 东北石油大学 2019-07-26 CN claimed
CN-109790179-A Composition for hardening soft tissue 加图立大学校产学协力团 2019-05-21 CN claimed
CN-108745838-A A kind of trailer coating spraying process 安徽强盛交通设备制造有限公司 2018-11-06 CN claimed
CN-108715715-A A kind of trailer surface anticorrosion coating 安徽强盛交通设备制造有限公司 2018-10-30 CN claimed
CN-108463894-A Organic electroluminescent device 国立大学法人九州大学 2018-08-28 CN claimed
CN-103489890-B Organic light-emitting display device and its manufacture method 三星显示有限公司 2018-02-06 CN claimed
CN-105348191-B A kind of method for directly preparing pure 8 oxyquinoline calcium 南昌航空大学 2018-01-16 CN claimed
CN-107527742-A Electrolyte for low-corrosivity electrolytic capacitor and manufacturing method thereof 肇庆市华胜电子有限公司 2017-12-29 CN claimed
CN-107382836-A A kind of preparation method of the ketone of 1 (4 aminophenyl) 1H pyridines 2 吴赣药业(苏州)有限公司 2017-11-24 CN claimed
CN-107251209-A Manufacture method, flip-chip fixing body and the first supply-type underfill resin combination of flip-chip fixing body 纳美仕有限公司 2017-10-13 CN claimed
CN-107163685-A A kind of preparation method of ink-jet printed Thief zone reactive dye ink 绍兴柯桥越强助剂有限公司 2017-09-15 CN claimed
CN-206298547-U One kind discoloration electrophoresis particle and electrophoretic display device (EPD) 广州奥翼电子科技股份有限公司 2017-07-04 CN claimed
CN-106520111-A Color-changing electrophoretic particle, preparation method thereof and electrophoretic display 广州奥翼电子科技股份有限公司 2017-03-22 CN claimed
CN-106084729-A A kind of conductive material and preparation technology thereof 合肥浦尔菲电线科技有限公司 2016-11-09 CN claimed
CN-105860449-A Amidated PBT material and preparation method thereof 滁州优胜高分子材料有限公司 2016-08-17 CN claimed