Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798739 | 0.92 | KCNH2 (0.37) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5457689 | 0.87 | KCNH2 (0.45) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5802639 | 0.84 | KCNH2 (0.36) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5455620 | 0.79 | KCNH2 (0.46) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5455435 | 0.78 | KCNH2 (0.43) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5450712 | 0.77 | KCNH2 (0.49) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14443939 | 0.77 | KCNH2 (0.49) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5801347 | 0.75 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL5457726 | 0.75 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL5463184 | 0.75 | KCNH2 (0.44) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |