Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799117 | 0.83 | POLB (0.59) | POLBNPC1MAPK1HSD17B10CA12 | |
| SCHEMBL5799115 | 0.83 | POLB (0.59) | POLBNPC1MAPK1HSD17B10CA12 | |
| SCHEMBL5807116 | 0.82 | POLB (0.58) | POLBNPC1MAPK1HSD17B10CA12 | |
| SCHEMBL5807113 | 0.82 | POLB (0.58) | POLBNPC1MAPK1HSD17B10CA12 | |
| SCHEMBL5808190 | 0.80 | GAA (0.45) | NPC1HSD17B10GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL29236542 | 0.79 | NPC1 (0.74) | POLBNPC1MAPK1HSD17B10CA12 | |
| SCHEMBL5795629 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2HTTALDH1A1MAPTLMNA | |
| SCHEMBL5636113 | 0.73 | KMT2A (0.64) | POLBNPC1MAPK1HSD17B10GAA | |
| SCHEMBL14597968 | 0.73 | HDAC1 (0.67) | POLBMAPK1HSD17B10CA9PTPN1 | |
| SCHEMBL11099529 | 0.72 | CA12 (0.48) | NPC1CA12CA9SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |