⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903076 | 0.76 | — | — | |
| SCHEMBL17925957 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL28953718 | 0.73 | — | — | |
| SCHEMBL31595667 | 0.72 | — | — | |
| SCHEMBL27884176 | 0.71 | — | — | |
| SCHEMBL27909178 | 0.71 | — | — | |
| SCHEMBL3123589 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL28953717 | 0.69 | — | — | |
| SCHEMBL6484964 | 0.68 | — | — | |
| SCHEMBL3660058 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104105690-A | Cyclic urea derivatives as androgen receptor antagonists | NOVARTIS AG | 2014-10-15 | — | — | CN | disclosed |
| EP-2416657-A1 | SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS FOR USE THEREOF | Medivation Prostate Therapeutics, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010118354-A1 | SUBSTITUTED DI-ARYLHYDANTOIN AND DI-ARYLTHIOHYDANTOIN COMPOUNDS AND METHODS FOR USE THEREOF | MEDIVATION PROSTATE THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |