Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 4/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5825071 | 0.85 | PDGFRA (0.59) | PDGFRAKDRSRCTGFBR1PDGFRB | |
| SCHEMBL5824451 | 0.79 | PDGFRA (0.66) | PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL5825445 | 0.78 | PDGFRA (0.59) | PDGFRAKDRAXLSRCPDGFRB | |
| SCHEMBL5824390 | 0.76 | AXL (0.56) | PDGFRAKDRAXLPDGFRBFGFR2 | |
| SCHEMBL12444104 | 0.76 | PDGFRA (0.76) | PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL5826205 | 0.75 | PDGFRA (0.52) | PDGFRAKDRAXLSRCTGFBR1 | |
| SCHEMBL5824511 | 0.75 | PDGFRA (0.56) | PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL5825827 | 0.74 | FGFR2 (0.63) | PDGFRAKDRAXLPDGFRBFGFR2 | |
| SCHEMBL5825801 | 0.74 | PDGFRA (0.66) | PDGFRAKDRPDGFRBFGFR2 | |
| SCHEMBL5824659 | 0.74 | FGFR2 (0.50) | PDGFRAKDRAXLPDGFRBFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | claimed |