Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826297 | 1.00 | BLM (0.36) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL208195 | 0.87 | — | — | |
| SCHEMBL5826288 | 0.82 | BLM (0.38) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL28849721 | 0.82 | BLM (0.42) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL5826298 | 0.82 | BLM (0.38) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL23222271 | 0.80 | BLM (0.36) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL29879121 | 0.80 | BLM (0.36) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL7623228 | 0.80 | BLM (0.36) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL25208953 | 0.78 | BLM (0.35) | BLMPMP22HSD17B10CA2CA12 | |
| SCHEMBL19002253 | 0.78 | BLM (0.35) | BLMPMP22HSD17B10CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060120971-A1 | Agents and methods for administration to the central nervous system | SIGNUM PHARMACEUTICALS, INC. | 2006-06-08 | — | — | US | disclosed |
| WO-2006041922-A2 | AGENTS AND METHODS FOR ADMINISTRATION TO THE CENTRAL NERVOUS SYSTEM | DARA BIOSCIENCES, INC. (US) | 2006-04-20 | — | — | WO | disclosed |
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | disclosed |
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | disclosed |