SCHEMBL5828215

SCHEMBL5828215

CCOC(=O)CC(C(=O)O)C(C)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
ALDH1A1 P00352 6/20 0.40
TRPA1 O75762 1/20 0.40
TSHR P16473 2/20 0.38
ALOX15 P16050 3/20 0.38
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 2/20 0.37
CHRM1 P11229 1/20 0.37
ADORA1 P30542 1/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29848264 0.89 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8653303 0.87 MGAM (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28303656 0.86 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL2637863 0.86 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7976835 0.86 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL6670672 0.84 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL6668710 0.82 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
Lactic Acid SCHEMBL29124782 0.82 TP53 (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL15788147 0.81 MGAM (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL76382 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103427-A High selectivity and high CO resistance for gas separation2Plasticized polymeric films 环球油品有限责任公司 2024-05-28 CN disclosed
US-11985974-B2 Antimicrobial ferulic acid derivatives and uses thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-05-21 US disclosed
CN-116615280-A High selectivity polyimide/PES blend hollow fiber membrane for gas separation 环球油品有限责任公司 2023-08-18 CN disclosed
CN-110636895-B Co-casting thin film composite flat membrane 环球油品有限责任公司 2022-07-05 CN disclosed
CN-107683305-B Microporous polymer composition 联邦科学与工业研究组织 2020-09-18 CN disclosed
CN-110636895-A Co-casting thin film composite flat membrane 环球油品有限责任公司 2019-12-31 CN disclosed
CN-105555838-B For the self-crosslinkable of separation and the aromatic polyimide film through self-crosslinking 环球油品公司 2018-06-08 CN disclosed
CN-107683305-A Microporous polymer compositions 联邦科学与工业研究组织 2018-02-09 CN disclosed
CN-106795180-A The mixed substrate membrane containing nano-grade molecular sieve of the modified and prepared therefrom azide crosslinking of zeolite imidazole ester skeleton 沙特基础工业全球技术公司 2017-05-31 CN disclosed
CN-106255544-A UV processes and the polymeric film of heat treatment 沙特基础工业全球技术公司 2016-12-21 CN disclosed
US-6153396-A DRUG SCREENING BY ADDING COMPOUND TO MIXTURE OF CHAPERONE AND PILUS SUBUNIT AND DETERMINING THE CHANGE IN BINDING; BACTERICIDES FOR URINARY TRACT INFECTIONS SIGA PHARMACEUTICALS, INC. (US) 2000-11-28 US disclosed
US-6001823-A NOVEL PYRANOSIDES WHICH ARE BELIEVED TO BE CAPABLE OF INTERACTING WITH PERIPLASMIC MOLECULAR CHAPERONES WASHINGTON UNIVERSITY 1999-12-14 US disclosed
EP-0730601-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS WASHINGTON UNIVERSITY (US) 1996-09-11 EP disclosed
WO-1995014028-A9 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS 1995-08-10 WO disclosed
WO-1995014028-A2 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS WASHINGTON UNIVERSITY (US) 1995-05-26 WO disclosed
US-4341776-A BACTERICIDES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1982-07-27 US disclosed
US-4328224-A ANTIBIOTICS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1982-05-04 US disclosed
US-4301161-A BACTERICIDES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1981-11-17 US disclosed
US-4298605-A ANTIBIOTICS, BACTERICIDES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1981-11-03 US disclosed
US-4229348-A Penicillanic acid derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11985974-B2 Antimicrobial ferulic acid derivatives and uses thereof FER, MGAM, DDOST MGAM 2/4885GAA 177/4885SI 136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.