Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482683 | 1.00 | PPARA (0.51) | PPARACA1CTSSCA2CA7 | |
| SCHEMBL26985920 | 0.89 | CA1 (0.55) | PPARACA1CTSSCA2CA7 | |
| SCHEMBL19215337 | 0.88 | PPARA (0.46) | PPARACA1CTSSNPC1PPARG | |
| SCHEMBL5744906 | 0.85 | PPARA (0.49) | PPARACA1CTSSNPC1PPARG | |
| SCHEMBL6482663 | 0.83 | CA1 (0.51) | PPARACA1CTSSCA2CA7 | |
| SCHEMBL2340083 | 0.83 | CA1 (0.51) | PPARACA1CTSSCA2CA7 | |
| SCHEMBL6495557 | 0.83 | CA1 (0.51) | PPARACA1CTSSCA2CA7 | |
| SCHEMBL7582347 | 0.82 | CA1 (0.57) | CA1CA2CA7CA9NPC1 | |
| SCHEMBL7572323 | 0.82 | CA1 (0.57) | CA1CA2CA7CA9NPC1 | |
| SCHEMBL7082464 | 0.82 | POLB (0.48) | CTSSADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105087684-A | Preparation method of tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate | LIANYUNGANG HONGYE CHEMICAL CO LTD | 2015-11-25 | — | — | CN | disclosed |
| US-RE39333-E1 | Process for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives | KANEKA CORPORATION (JP) | 2006-10-10 | — | — | US | disclosed |
| EP-1104750-B1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORP (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6340767-B1 | REACTION OF LITHIUM AMIDE WITH ACETIC ACID ESTER AND HYDROXY PROPIONIC ACID | KANEKA CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1104750-A1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2001-06-06 | — | — | EP | disclosed |