Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL5829331

CCCCCCC(CCS)C(=O)O.CCCCCCC(CCS)C(=O)O.CCCCCCC(CCS)C(=O)O.CCCCCCC(CCS)C(=O)O.C[Sn].C[Sn].S.S

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.53
GRIK2 Q13002 2/20 0.53
FOLH1 Q04609 4/20 0.51
CA2 P00918 2/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
MAPK1 P28482 1/20 0.50
GPR84 Q9NQS5 3/20 0.48
FFAR1 O14842 1/20 0.48
MAPT P10636 1/20 0.47
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
CHRM1 P11229 1/20 0.47
AKR1A1 P14550 1/20 0.47
CHRM3 P20309 1/20 0.47
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
ADRA1A P35348 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11288996 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL9777682 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL11704362 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL11295428 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL4455550 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL4454959 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL11598279 0.94 GRIK1 (0.58) GRIK1GRIK2FOLH1CA2SLC1A2
Hydrogen Sulfide SCHEMBL11417520 0.88 GRIK1 (0.49) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL15254473 0.87 FOLH1 (0.67) GRIK1GRIK2FOLH1CA2SLC1A2
SCHEMBL11356676 0.87 FOLH1 (0.67) GRIK1GRIK2FOLH1CA2SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041265-B2 Alkaline earth metal-basic silicate particle MIZUSAWA INDUSTRIAL CHEMICALS (JP) 2006-05-09 US disclosed
US-20040147660-A1 Alkaline earth metal-basic silicate particle MIZUSAWA INDUSTRIAL CHEMICALS (JP) 2004-07-29 US disclosed