⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358674 | 1.00 | — | — | |
| SCHEMBL9906088 | 1.00 | — | — | |
| SCHEMBL11322858 | 0.88 | KMT2A (0.43) | — | |
| SCHEMBL19340310 | 0.84 | — | — | |
| SCHEMBL859458 | 0.80 | — | — | |
| SCHEMBL61228 | 0.80 | — | — | |
| SCHEMBL68935 | 0.80 | — | — | |
| SCHEMBL258995 | 0.80 | — | — | |
| SCHEMBL12309138 | 0.78 | SLC6A2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL31395319 | 0.78 | CYP2D6 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106361-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2022-04-07 | — | — | US | disclosed |
| WO-2015084850-A1 | MEMBRANE TRANSLOCATION ASSAY FOR SIRNA | SIRNA THERAPEUTICS, INC. (US) | 2015-06-11 | — | — | WO | disclosed |
| WO-2015069587-A2 | PEPTIDE CONTAINING CONJUGATES FOR DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015069586-A2 | DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES AND PEPTIDE CONTAINING CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015034920-A2 | GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR COMPOSITIONS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2014088920-A1 | DISULFIDE MASKED PRODRUG COMPOSITIONS AND METHODS | MERCK SHARP & DOHME CORP. (US) | 2014-06-12 | — | — | WO | disclosed |
| US-8357638-B2 | Oligonucleotide library encoding randomised peptides | ASTON UNIVERSITY (GB) | 2013-01-22 | — | — | US | disclosed |
| US-20100081786-A1 | Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-01 | — | — | US | disclosed |
| US-20090264313-A1 | Oligonucleotide library encoding randomised peptides | ASTON UNIVERSITY (GB) | 2009-10-22 | — | — | US | disclosed |
| US-7541143-B2 | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples | ONCOIMMUNIN, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7307148-B2 | Method for purification of albumin conjugates | CONJUCHEM BIOTECHNOLOGIES INC. (CA) | 2007-12-11 | — | — | US | disclosed |
| US-20070280939-A1 | Prostatic Acid Phosphatase Antigens | NOTTINGHAM TRENT UNIVERSITY, THE (GB) | 2007-12-06 | — | — | US | disclosed |
| US-20070243562-A1 | Lectins for Analyzing Sugar Chains and Method of Using the Same | SUMMIT GLYCORESEARCH CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |
| US-7108876-B2 | Shaped cheese reconstruction with transglutaminase | NUTRICEPTS, INC. (US) | 2006-09-19 | — | — | US | disclosed |
| US-20020106423-A1 | Shaped cheese reconstruction with transglutaminase | NUTRICEPTS, INC. | 2002-08-08 | — | — | US | disclosed |
| US-5928689-A | Method for treating PSE meat with transglutaminase | KRAFT FOODS, INC. (US) | 1999-07-27 | — | — | US | disclosed |