Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583203 | 0.93 | PDE4B (0.44) | PDE4BPDE7AADORA1ADORA2A | |
| SCHEMBL583211 | 0.92 | PDE4B (0.52) | PDE4BPDE7A | |
| SCHEMBL582983 | 0.92 | PDE4B (0.48) | PDE4BPDE7AADORA1ADORA2A | |
| SCHEMBL583195 | 0.92 | PDE4B (0.54) | PDE4BPDE7A | |
| SCHEMBL583682 | 0.90 | PDE4B (0.43) | PDE4BPDE7AADORA1 | |
| SCHEMBL582971 | 0.89 | PDE4B (0.49) | PDE4BPDE7AADORA1ADORA2A | |
| SCHEMBL582300 | 0.89 | PDE4B (0.48) | PDE4BPDE7AADORA1ADORA2A | |
| SCHEMBL583298 | 0.88 | PDE4B (0.45) | PDE4BPDE7AADORA1ADORA2A | |
| SCHEMBL582876 | 0.88 | PDE4B (0.45) | PDE4BPDE7AADORA1ADORA2A | |
| SCHEMBL582749 | 0.88 | PDE4B (0.47) | PDE4BPDE7AADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124944-B1 | Pyrazolo[3,4-b]pyridine derivatives as phosphodiesterase inhibitors | RANBAXY LAB LTD (IN) | 2012-02-15 | — | — | EP | claimed |