Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 18/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 14/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 14/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198450 | 0.86 | ITGAL (0.53) | ITGALITGB2ICAM1 | |
| SCHEMBL5830434 | 0.83 | ITGAL (0.51) | ITGALITGB2ICAM1MAPT | |
| SCHEMBL6199246 | 0.83 | ITGAL (0.64) | ITGALITGB2ICAM1 | |
| SCHEMBL6196483 | 0.82 | ITGAL (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL6201362 | 0.82 | ITGAL (0.60) | ITGALITGB2ICAM1 | |
| SCHEMBL6199341 | 0.81 | ITGAL (0.61) | ITGALITGB2ICAM1 | |
| SCHEMBL5830861 | 0.80 | ITGAL (0.64) | ITGALITGB2ICAM1ENPP2 | |
| SCHEMBL6310173 | 0.80 | ITGAL (0.53) | ITGALITGB2ICAM1 | |
| SCHEMBL6199876 | 0.79 | ITGAL (0.55) | ITGALITGB2ICAM1 | |
| SCHEMBL5830177 | 0.79 | ITGAL (0.53) | ITGALITGB2ICAM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39197-E1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2006-07-18 | — | — | US | disclosed |