Tetrahydrofuran

Tetrahydrofuran

SCHEMBL5831073

C1CCOC1.CC=Cc1c(O)cccc1CCCCCCCCCCCC

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.45
MCL1 Q07820 6/20 0.45
BCL2L1 Q07817 5/20 0.45
BAK1 Q16611 5/20 0.45
KAT8 Q9H7Z6 3/20 0.45
SAE1 Q9UBE0 2/20 0.45
EP300 Q09472 2/20 0.45
KAT5 Q92993 2/20 0.45
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
KAT2A Q92830 1/20 0.45
KAT2B Q92831 1/20 0.45
F7 P08709 3/20 0.43
F3 P13726 3/20 0.43
MMP2 P08253 2/20 0.43
MAPT P10636 2/20 0.43
ALOX15 P16050 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ECE1 P42892 1/20 0.43
SGMS1 Q86VZ5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL9356146 0.94 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
Oxirane SCHEMBL5831076 0.94 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
Oxirane SCHEMBL5830127 0.94 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL29366438 0.89 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL7180164 0.89 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL7175266 0.89 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL7622564 0.89 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
Oxirane SCHEMBL5830545 0.82 TYR (0.47) BIDMCL1BCL2L1BAK1KAT8
Tetrahydrofuran SCHEMBL11762936 0.81 BID (0.50) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL29363173 0.77 TYR (0.53) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113993927-A Low temperature curable composition 盛势达技研株式会社 2022-01-28 CN disclosed
US-7138455-B2 Acrylic polymer powder, acrylic sol and molding KURARAY CO., LTD. (JP) 2006-11-21 US disclosed
US-20040147668-A1 Acrylic polymer powder, acrylic sol and molding KURARAY CO., LTD. (JP) 2004-07-29 US disclosed
EP-1440997-A1 Acrylic polymer powder, acrylic sol and molding KURARAY CO., LTD. (JP) 2004-07-28 EP disclosed
US-5324862-A Adduct of an alkylene oxide and a propenylphenol or a propenylphenol modified polyether DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1994-06-28 US disclosed