Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 1.00 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832916 | 0.86 | SLC6A4 (0.76) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| SCHEMBL5833353 | 0.86 | SLC6A4 (0.76) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| SCHEMBL1643390 | 0.79 | SLC6A4 (0.70) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| SCHEMBL1645253 | 0.79 | SLC6A4 (0.65) | SLC6A4ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL1645171 | 0.78 | SLC6A4 (0.64) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| SCHEMBL5833050 | 0.78 | SLC6A4 (0.76) | SLC6A4PDE7ASLC6A2SLC6A3 | |
| SCHEMBL235621 | 0.78 | SLC6A4 (0.64) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| SCHEMBL5832891 | 0.78 | SLC6A4 (0.64) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| SCHEMBL1645187 | 0.78 | SLC6A4 (0.64) | SLC6A4PDE7AALDH1A1MAPTHPGD | |
| Trifluoromethanesulfonic Acid SCHEMBL1110840 | 0.77 | SLC6A4 (0.62) | SLC6A4PDE7AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041851-B2 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-05-09 | — | — | US | disclosed |
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-12-25 | — | — | US | disclosed |
| WO-2003078393-A2 | FLUORINATED PHENYL THIOPHENYL DERIVATIVES AND THEIR USE FOR IMAGING SEROTONIN TRANSPORTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | SLC6A4, SLCO4C1, SLC6A2 | SLC6A4 1/4885PDE7A 1594/4885ALDH1A1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.