Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 16/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312383 | 1.00 | KDM4E (0.36) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL13766206 | 1.00 | KDM4E (0.36) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL5837635 | 1.00 | KDM4E (0.36) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12124389 | 1.00 | KDM4E (0.36) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL5833238 | 1.00 | KDM4E (0.36) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL15975762 | 0.94 | PDK2 (0.32) | PDK2 | |
| SCHEMBL5833423 | 0.94 | KDM4E (0.39) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL24293153 | 0.92 | PDK2 (0.33) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12124336 | 0.92 | PDK2 (0.42) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL13766219 | 0.92 | PDK2 (0.48) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064228-B1 | Spiro silane compound and organic electroluminescent device using the same | AU OPTRONICS CORP. (TW) | 2006-06-20 | — | — | US | claimed |
| US-7064228-B1 | Spiro silane compound and organic electroluminescent device using the same | AU OPTRONICS CORP. (TW) | 2006-06-20 | — | — | US | disclosed |