⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827359 | 0.78 | — | — | |
| SCHEMBL12289687 | 0.78 | — | — | |
| SCHEMBL12223046 | 0.78 | — | — | |
| SCHEMBL4966905 | 0.69 | — | — | |
| SCHEMBL25910764 | 0.68 | — | — | |
| SCHEMBL4240469 | 0.67 | — | — | |
| SCHEMBL24584387 | 0.67 | — | — | |
| SCHEMBL13650772 | 0.67 | — | — | |
| SCHEMBL18968869 | 0.67 | — | — | |
| SCHEMBL6982703 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317430-B1 | (2-AZABICYCLO [2.2.1]HEPT-7-YL)METHANOL DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | MERCK PATENT GMBH (DE) | 2005-05-18 | — | — | EP | claimed |
| US-20040039045-A1 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2004-02-26 | — | — | US | claimed |
| US-7008955-B2 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | disclosed |
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | MERCK PATENT GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
| US-20040039045-A1 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-1379502-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | MERCK PATENT GmbH (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083640-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |