SCHEMBL5833495

SCHEMBL5833495

CCCC1=Cc2ccccc2C1[Zr](Cl)(Cl)C1C(CCC)=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194669 0.90 CYP3A4 (0.32)
SCHEMBL2519661 0.86 CYP11B1 (0.30)
SCHEMBL1130237 0.83
SCHEMBL22228411 0.79
SCHEMBL22228404 0.78
SCHEMBL815326 0.75 CYP11B1 (0.31)
SCHEMBL22228292 0.75
Bromide SCHEMBL27203210 0.75
SCHEMBL812473 0.75
SCHEMBL1131505 0.74 CYP2D6 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3058002-B1 POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE BASELL POLYOLEFINE GMBH (DE) 2019-08-21 EP disclosed
US-9671047-B2 Polyethylene of raised temperature resistance BASELL POLYOLEFINE GMBH (DE) 2017-06-06 US disclosed
US-20160298795-A1 POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE BASELL POLYOLEFINE GMBH (DE) 2016-10-13 US disclosed
EP-3058002-A1 POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE Basell Polyolefine GmbH (DE) 2016-08-24 EP disclosed
WO-2015055392-A1 POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE BASELL POLYOLEFINE GMBH (DE) 2015-04-23 WO disclosed
US-7141632-B2 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator UNIVATION TECHNOLOGIES, LLC (US) 2006-11-28 US disclosed
US-7060765-B2 Low comonomer incorporating metallocene catalyst compounds UNIVATION TECHNOLOGIES, LLC (US) 2006-06-13 US disclosed
US-6828394-B2 Used for copolymerizing ethylene to form a copolymer having a bimodal molecular weight distribution UNIVATION TECHNOLOGIES, LLC 2004-12-07 US disclosed
US-20040225088-A1 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator VAUGHAN GEORGE ALAN (US) 2004-11-11 US disclosed
EP-1412400-A2 MIXED METALLOCENE CATALYST SYSTEMS CONTAINING A POOR COMONOMER INCORPORATOR AND A GOOD COMONOMER INCORPORATOR Univation Technologies LLC (US) 2004-04-28 EP disclosed
EP-1412394-A2 LOW COMONOMER INCORPORATING METALLOCENE CATALYST COMPOUNDS Univation Technologies LLC (US) 2004-04-28 EP disclosed
US-20040077785-A1 Low comonomer incorporating metallocene catalyst compounds UNIVATION TECHNOLOGIES, LLC 2004-04-22 US disclosed
US-20030088038-A1 Mixed metallocene catalyst systems containing a poor comonomer incorporator and a good comonomer incorporator UNIVATION TECHNOLOGIES, LLC 2003-05-08 US disclosed
WO-2003008465-A2 LOW COMONOMER INCORPORATING METALLOCENE CATALYST COMPOUNDS UNIVATION TECHNOLOGIES, LLC (US) 2003-01-30 WO disclosed
WO-2003008468-A2 MIXED METALLOCENE CATALYST SYSTEMS CONTAINING A POOR COMONOMER INCORPORATOR AND A GOOD COMONOMER INCORPORATOR UNIVATION TECHNOLOGIES, LLC (US) 2003-01-30 WO disclosed
US-6391991-B1 USING COORDINATION POLYMERIZATION CATALYST BASELL TECHNOLOGY COMPANY BV (NL) 2002-05-21 US disclosed
EP-0693506-B1 Process for the preparation of amorphous polymers of propylene BASELL TECHNOLOGY CO BV (NL) 2001-08-29 EP disclosed
EP-0693506-A2 Process for the preparation of amorphous polymers of propylene SPHERILENE S.p.A. (IT) 1996-01-24 EP disclosed