Pyridine

Pyridine

SCHEMBL5833723

N.[Pt].c1ccncc1.c1ccncc1.c1ccncc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.82
NAPRT Q6XQN6 1/20 0.82
TDP1 Q9NUW8 1/20 0.82
NOTUM Q6P988 1/20 0.37
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL8944311 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL3270376 0.95
Pyridine SCHEMBL10896218 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL346198 0.95
Pyridine SCHEMBL1626309 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Benzene SCHEMBL23044989 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL4530165 0.95
Pyridine SCHEMBL4610071 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL1310722 0.95 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL1948151 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7005532-B2 Process of producing alkoxysilanes TOAGOSEI CO., LTD. (JP) 2006-02-28 US disclosed
US-20050020845-A1 Process of producing alkoxysilanes TOAGOSEI CO., LTD. (JP) 2005-01-27 US disclosed
EP-1428828-A1 PROCESS FOR PREPARATION OF ALKOXYSILANES TOAGOSEI CO., LTD. (JP) 2004-06-16 EP disclosed