Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.79 |
| ▸ | HPGD | P15428 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL2146545 | 1.00 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL27953278 | 0.97 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL22158684 | 0.97 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL28102809 | 0.97 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL2536972 | 0.97 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL1091906 | 0.95 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid SCHEMBL1373727 | 0.95 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Benzene SCHEMBL28121594 | 0.95 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Methyl Ester SCHEMBL21623864 | 0.94 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Benzene SCHEMBL28206424 | 0.94 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746439-B | Preparation method of end group functionalized acrylonitrile homopolymer or copolymer | UNIV EAST CHINA SCIENCE & TECH | 2014-03-26 | — | — | CN | disclosed |
| US-7094833-B2 | Block copolymer | KANEKA CORPORATION | 2006-08-22 | — | — | US | disclosed |
| US-20040236020-A1 | Block copolymer | KANEKA CORPORATION (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1411070-A1 | BLOCK COPOLYMER | KANEKA CORPORATION (JP) | 2004-04-21 | — | — | EP | disclosed |