Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582548 | 0.93 | POLB (0.49) | POLBPDE4BPDE7AKMT2ASSTR5 | |
| SCHEMBL583872 | 0.93 | POLB (0.48) | POLBPDE4BPDE7AKMT2A | |
| SCHEMBL583261 | 0.93 | POLB (0.51) | POLBPDE4BPDE7AKMT2ASSTR5 | |
| SCHEMBL582564 | 0.92 | POLB (0.47) | POLBPDE4BPDE7A | |
| SCHEMBL582581 | 0.91 | POLB (0.49) | POLBPDE4BPDE7AKMT2AADORA1 | |
| SCHEMBL583062 | 0.91 | POLB (0.50) | POLBPDE4BPDE7AKMT2ASSTR5 | |
| SCHEMBL583187 | 0.91 | POLB (0.50) | POLBPDE4BPDE7AKMT2ASSTR5 | |
| SCHEMBL582938 | 0.91 | POLB (0.46) | POLBPDE4BPDE7AKMT2A | |
| SCHEMBL583182 | 0.90 | POLB (0.48) | POLBPDE4BPDE7AKMT2A | |
| SCHEMBL582379 | 0.90 | POLB (0.49) | POLBPDE4BPDE7AKMT2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124944-B1 | Pyrazolo[3,4-b]pyridine derivatives as phosphodiesterase inhibitors | RANBAXY LAB LTD (IN) | 2012-02-15 | — | — | EP | claimed |