Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582568 | 1.00 | PDE4B (0.48) | PDE4BADORA1ADORA2APDE5AHTT | |
| SCHEMBL582569 | 1.00 | PDE4B (0.48) | PDE4BADORA1ADORA2APDE5AHTT | |
| SCHEMBL582223 | 0.85 | PDE4B (0.51) | PDE4BADORA1ADORA2APDE5AHTT | |
| SCHEMBL1472464 | 0.76 | PDE4B (0.54) | PDE4BADORA1HTT | |
| SCHEMBL583577 | 0.76 | PDE4B (0.54) | PDE4BADORA1HTT | |
| SCHEMBL583013 | 0.74 | PDE4B (0.60) | PDE4BHTT | |
| SCHEMBL1471895 | 0.74 | PDE4B (0.60) | PDE4BHTT | |
| SCHEMBL7028354 | 0.74 | KMT2A (0.60) | PDE4BADORA1HTTLMNAALDH1A1 | |
| SCHEMBL582654 | 0.73 | PDE4B (0.60) | PDE4B | |
| SCHEMBL582653 | 0.73 | PDE4B (0.60) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124944-B1 | Pyrazolo[3,4-b]pyridine derivatives as phosphodiesterase inhibitors | RANBAXY LAB LTD (IN) | 2012-02-15 | — | — | EP | claimed |