⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101538 | 0.71 | — | — | |
| SCHEMBL321837 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28710384 | 0.69 | — | — | |
| SCHEMBL11096889 | 0.66 | — | — | |
| SCHEMBL11096888 | 0.66 | — | — | |
| SCHEMBL872865 | 0.57 | — | — | |
| SCHEMBL31059 | 0.53 | — | — | |
| SCHEMBL279754 | 0.53 | — | — | |
| SCHEMBL21785045 | 0.53 | CRBN (0.47) | — | |
| SCHEMBL31052755 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621830-A | Double-targeting polyhydroxy alkaloid compound and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2023-08-22 | — | — | CN | disclosed |
| US-7026334-B1 | Thiazolidine compounds and pharmaceutical compositions exhibiting thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2006-04-11 | — | — | US | disclosed |
| EP-1207155-A1 | DRUG COMPOSITIONS EXHIBITING THROMBOPOIETIN AGONISM | SHIONOGI & CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0224515-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007360-A1 | SUBSTITUTED THIAZOLIDINYL ETHER | CIBA-GEIGY AG (CH) | 1986-12-18 | — | — | WO | disclosed |