Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 3/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835468 | 0.93 | TBXA2R (0.35) | TBXA2R | |
| SCHEMBL5775915 | 0.80 | TBXA2R (0.45) | TBXA2R | |
| SCHEMBL5779059 | 0.79 | GRM2 (0.33) | — | |
| SCHEMBL5836332 | 0.79 | TBXA2R (0.39) | TBXA2R | |
| SCHEMBL5835920 | 0.79 | TBXA2R (0.39) | TBXA2R | |
| SCHEMBL5836476 | 0.78 | RHEB (0.31) | — | |
| SCHEMBL5772752 | 0.76 | TBXA2R (0.42) | TBXA2R | |
| SCHEMBL5778018 | 0.75 | TBXA2R (0.51) | TBXA2R | |
| SCHEMBL5776742 | 0.75 | TBXA2R (0.51) | TBXA2R | |
| SCHEMBL5778328 | 0.70 | TBXA2R (0.46) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |