⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726128 | 0.84 | — | — | |
| SCHEMBL6536131 | 0.84 | — | — | |
| SCHEMBL31402449 | 0.80 | — | — | |
| SCHEMBL19460536 | 0.75 | — | — | |
| SCHEMBL2775347 | 0.65 | POLB (0.39) | — | |
| SCHEMBL12226143 | 0.65 | — | — | |
| SCHEMBL11068637 | 0.65 | — | — | |
| SCHEMBL11138176 | 0.62 | — | — | |
| SCHEMBL2471351 | 0.61 | — | — | |
| SCHEMBL459206 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030652-A1 | SUBSTITUTED SPIRODIENES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | claimed |
| CN-115385948-A | Spiro-dihydrobenzothiole bisoxazoline compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2022-11-25 | — | — | CN | disclosed |
| US-10005947-B2 | Modified hydrocarbon resins as fluid loss additives | INGEVITY SOUTH CAROLINA, LLC (US) | 2018-06-26 | — | — | US | disclosed |
| EP-3071782-A1 | MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES | Georgia-Pacific Chemicals LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077215-A1 | MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20150136402-A1 | MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2015-05-21 | — | — | US | disclosed |
| US-7091344-B2 | Infrared chromophores | SILVERBROOK RESEARCH PTY LTD (AU) | 2006-08-15 | — | — | US | disclosed |
| US-20020136972-A1 | Infrared chromophores | SILVERBROOK RESEARCH PTY. LTD. (AU) | 2002-09-26 | — | — | US | disclosed |
| WO-2002014438-A1 | INFRARED CHROMOPHORES | SILVERBROOK RESEARCH PTY LTD (AU) | 2002-02-21 | — | — | WO | disclosed |
| WO-1995030652-A1 | SUBSTITUTED SPIRODIENES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | disclosed |
| US-4433100-A | DICYCLOPENTADIENE, NON-AROMATIC UNSATURATED HYDROCARBON, FATTY OR ROSIN ACID | NEVILLE CHEMICAL COMPANY (US) | 1984-02-21 | — | — | US | disclosed |