⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158070 | 0.72 | PARP1 (0.52) | — | |
| SCHEMBL170542 | 0.68 | MAPKAPK2 (0.39) | — | |
| SCHEMBL6104267 | 0.67 | PARP1 (0.41) | — | |
| SCHEMBL196628 | 0.65 | — | — | |
| SCHEMBL130169 | 0.65 | — | — | |
| SCHEMBL453001 | 0.65 | — | — | |
| SCHEMBL449578 | 0.65 | — | — | |
| SCHEMBL22950 | 0.65 | — | — | |
| SCHEMBL184167 | 0.65 | — | — | |
| SCHEMBL71856 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3488 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| WO-2024009308-A1 | TRPV2 CHANNEL BLOCKERS AND USE THEREOF | ICHILOV TECH LTD. (IL) | 2024-01-11 | — | — | WO | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| WO-2023107490-A1 | HETEROCYCLE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS | PRETZEL THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | claimed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-104892639-B | 3,6- bis- replaces [1,2,4] triazole [3,4-b] [1,3,4] thiadiazole compound and application thereof | 中国科学院上海药物研究所 | 2018-10-30 | — | — | CN | claimed |
| US-20180072705-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2018-03-15 | — | — | US | claimed |
| EP-2678331-B1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2016-04-27 | — | — | EP | claimed |
| CN-105531265-A | Pesticidal compounds | BASF SE | 2016-04-27 | — | — | CN | claimed |
| CN-104892639-A | 3,6-Disubstituted[1,2,4]triazolyl[3,4-b][1,3,4]thiadiazole compounds and use thereof | SHANGHAI INST MATERIA MEDICA | 2015-09-09 | — | — | CN | claimed |
| US-5278169-A | Method of treating or prevention of fibrillation of the heart | E. R. SQUIBB & SONS, INC. (US) | 1994-01-11 | — | — | US | claimed |
| US-5202330-A | Hypotensive and cardiovascular agent, reduces blood pressure in mammals | E. R. SQUIBB & SONS, INC. (US) | 1993-04-13 | — | — | US | claimed |
| EP-0511826-A2 | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1992-11-04 | — | — | EP | claimed |
| US-5143915-A | Hypotensive agents | E. R. SQUIBB & SONS, INC. (US) | 1992-09-01 | — | — | US | claimed |
| US-5140031-A | Pyranyl cyanoguanidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-08-18 | — | — | US | claimed |
| US-4900750-A | ANTICOAGULANTS; ENZYME INHIBITORS | JOHN WYETH & BROTHER, LIMITED (GB) | 1990-02-13 | — | — | US | claimed |
| EP-0253178-A1 | Substituted 1,5-benzodiazepine compounds | E.R. Squibb & Sons, Inc. (US) | 1988-01-20 | — | — | EP | claimed |
| US-4650797-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1987-03-17 | — | — | US | claimed |
| US-4647561-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1987-03-03 | — | — | US | claimed |
| EP-0204317-A2 | 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters | E.R. Squibb & Sons, Inc. (US) | 1986-12-10 | — | — | EP | claimed |