SCHEMBL5837547

SCHEMBL5837547

COC(=O)C1(CCC(=O)O)CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ADAM17 P78536 3/20 0.31
MAPT P10636 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837042 0.92 TSHR (0.33) CYP2D6CYP2C19ADAM17
SCHEMBL5837346 0.91 EPHX2 (0.33) CYP2D6CYP2C19
SCHEMBL5838282 0.89 TSHR (0.33) CYP2D6CYP2C19
SCHEMBL5836624 0.86 CYP2D6 (0.35) CYP2D6CYP2C19ADAM17
SCHEMBL11465814 0.85 CYP2D6 (0.35) CYP2D6CYP2C19ADAM17
SCHEMBL5836347 0.85 CYP2D6 (0.35) CYP2D6CYP2C19ADAM17MAPTSIGMAR1
SCHEMBL32689044 0.85 CYP2D6 (0.38) CYP2D6CYP2C19ADAM17MAPT
SCHEMBL11168238 0.85 CYP2D6 (0.35) CYP2D6CYP2C19ADAM17
SCHEMBL5837298 0.84 EPHX2 (0.35) CYP2D6CYP2C19
SCHEMBL5838040 0.83 TSHR (0.37) CYP2D6CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100386357-C Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORP (JP) 2008-05-07 CN disclosed
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
CN-1659205-A Norbornene-based ring-opening polymer, hydrogenation product of norbornene-based ring-opening polymer, and method for producing same ZEON CORP (JP) 2005-08-24 CN disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed