SCHEMBL5837751

SCHEMBL5837751

CCOC(=O)[C@@H]1[C@@H](C(=O)O)[C@H]2C=C[C@@H]1C2

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.69
ALDH1A1 P00352 5/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
LMNA P02545 1/20 0.55
RAB9A P51151 1/20 0.53
PPM1B O75688 1/20 0.51
PTPN1 P18031 1/20 0.51
PPP1CC P36873 1/20 0.51
TDP1 Q9NUW8 2/20 0.49
CASP6 P55212 1/20 0.49
HTT P42858 1/20 0.48
KDM4E B2RXH2 4/20 0.47
GAA P10253 1/20 0.47
APEX1 P27695 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19324112 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL7594331 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL19323400 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL29307701 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL5837756 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL19318634 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL19318637 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL27948552 1.00 POLB (0.69) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL1451358 0.93 POLB (0.57) POLBALDH1A1SMN1; SMN2LMNARAB9A
SCHEMBL19318635 0.93 POLB (0.57) POLBALDH1A1SMN1; SMN2LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed