SCHEMBL5837786

SCHEMBL5837786

CCOC(=O)C1(CCC(=O)OC)CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADAM17 P78536 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPK1 P28482 1/20 0.31
EPHX2 P34913 2/20 0.30
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
GAA P10253 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837438 0.93 EPHX2 (0.34) ADAM17CYP2D6CYP2C19EPHX2TSHR
SCHEMBL5837476 0.92 CYP2D6 (0.35) ADAM17CYP2D6CYP2C19MAPK1EPHX2
SCHEMBL5837298 0.90 EPHX2 (0.35) CYP2D6CYP2C19EPHX2GAA
SCHEMBL5838282 0.89 TSHR (0.33) CYP2D6CYP2C19EPHX2CA12CA2
SCHEMBL5836976 0.87 CYP2D6 (0.35) ADAM17CYP2D6CYP2C19MAPK1GAA
SCHEMBL5836624 0.87 CYP2D6 (0.35) ADAM17CYP2D6CYP2C19MAPK1
SCHEMBL5837412 0.84 TSHR (0.33) CYP2D6CYP2C19EPHX2CA12CA2
SCHEMBL32688640 0.83 AKT1 (0.35) ADAM17CYP2D6CYP2C19MAPK1
SCHEMBL32688968 0.82 CYP2D6 (0.42) ADAM17CYP2D6CYP2C19MAPK1LMNA
SCHEMBL5837479 0.82 CYP2D6 (0.35) CYP2D6CYP2C19EPHX2GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100386357-C Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORP (JP) 2008-05-07 CN disclosed
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
CN-1659205-A Norbornene-based ring-opening polymer, hydrogenation product of norbornene-based ring-opening polymer, and method for producing same ZEON CORP (JP) 2005-08-24 CN disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed