Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526318 | 0.81 | CYP1A2 (0.47) | CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL268253 | 0.81 | CYP1A2 (0.47) | CYP1A2CYP2D6 | |
| SCHEMBL707889 | 0.78 | CYP1A2 (0.62) | CYP1A2CYP2D6 | |
| SCHEMBL708799 | 0.78 | CYP1A2 (0.62) | CYP1A2CYP2D6 | |
| SCHEMBL706895 | 0.78 | CYP1A2 (0.62) | CYP1A2CYP2D6 | |
| SCHEMBL707888 | 0.78 | CYP1A2 (0.62) | CYP1A2CYP2D6 | |
| Carbimide SCHEMBL959898 | 0.77 | CYP1A2 (0.43) | CYP1A2CYP2D6 | |
| SCHEMBL5183227 | 0.75 | — | — | |
| SCHEMBL18245139 | 0.75 | CYP1A2 (0.31) | CYP1A2CYP2D6 | |
| SCHEMBL18133507 | 0.73 | CYP1A2 (0.58) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101974-B2 | TNF-αvariants | XENCOR (US) | 2006-09-05 | — | — | US | disclosed |
| US-20020110868-A1 | Design and discovery of protein based TNF-alpha variants for the treatment of TNF-alpha related disorders | XENCOR, INC. | 2002-08-15 | — | — | US | disclosed |