⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276388 | 0.74 | MEN1 (1.00) | — | |
| SCHEMBL2601892 | 0.71 | — | — | |
| SCHEMBL27566565 | 0.69 | MEN1 (0.35) | — | |
| SCHEMBL19420694 | 0.69 | MEN1 (0.75) | — | |
| SCHEMBL3613053 | 0.69 | — | — | |
| SCHEMBL11796900 | 0.69 | — | — | |
| SCHEMBL80295 | 0.69 | — | — | |
| SCHEMBL1753954 | 0.69 | MEN1 (0.56) | — | |
| SCHEMBL11640072 | 0.67 | — | — | |
| SCHEMBL8888486 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2416647-A2 | SAFENING AGENT | Taminco, Naamloze Vennootschap (BE) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116264-A2 | SAFENING AGENT | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2010-10-14 | — | — | WO | claimed |
| WO-2020245629-A1 | MIXTURES AND COMPOSITIONS OF FLUENSULFONE AND AUXIN, AND USES THEREOF | ADAMA MAKHTESHIM LTD> (IL) | 2020-12-10 | — | — | WO | disclosed |
| EP-2567964-B1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES INC (US) | 2015-02-11 | — | — | EP | disclosed |
| US-8552174-B2 | Solutions, methods, and processes for deprotection of polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2567964-A2 | Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection | Agilent Technologies, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| US-8202985-B2 | Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-7759471-B2 | nucleotide monomer used to make protected RNA that has similar stability to the DNA molecule | AGILENT TECHNOLOGIES, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2010-03-25 | — | — | US | disclosed |
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| EP-2001896-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | Agilent Technologies, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007112264-A2 | CLEAVABLE LINKERS FOR POLYNUCLEOTIDES | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007112263-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| EP-1792909-A1 | Synthesis of polynucleotides | Agilent Technologies, Inc. (US) | 2007-06-06 | — | — | EP | disclosed |
| US-20070100138-A1 | Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2007-05-03 | — | — | US | disclosed |
| US-20070100136-A1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES, INC. | 2007-05-03 | — | — | US | disclosed |
| US-20070100137-A1 | Solutions, methods, and processes for deprotection of polynucleotides | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2007-05-03 | — | — | US | disclosed |