Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383745 | 1.00 | KCNH2 (0.49) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4515182 | 1.00 | KCNH2 (0.49) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1384530 | 1.00 | KCNH2 (0.49) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4514077 | 1.00 | KCNH2 (0.49) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4527298 | 0.90 | KCNH2 (0.53) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1383633 | 0.90 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4512833 | 0.90 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1383642 | 0.90 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1382745 | 0.90 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4516797 | 0.89 | KCNH2 (0.52) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094780-B1 | 3-aminoquinazolin-2,4-dione antibacterial agents | WARNER LAMBERT COMPANY LLC (US) | 2006-08-22 | — | — | US | claimed |