Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CDC37 | Q16543 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5840768 | 0.99 | SLC1A2 (0.47) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL5841166 | 0.87 | SLC1A2 (0.46) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL5841578 | 0.86 | GRM2 (0.47) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL5840168 | 0.86 | SLC1A2 (0.45) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL5841613 | 0.85 | GRM2 (0.46) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL5841620 | 0.85 | GRM2 (0.46) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL6465474 | 0.85 | GRM2 (0.46) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL5841686 | 0.84 | GRM2 (0.45) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL5841488 | 0.83 | GRM8 (0.43) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL5839843 | 0.82 | SLC1A2 (0.42) | SLC1A2SLC1A1GRM8GRM6GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038077-B2 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050009912-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009912-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A3, SLC1A1 | SLC1A2 1/4885SLC1A1 3/4885GRM8 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.