SCHEMBL5841679

SCHEMBL5841679

CCC1(CC)c2ccccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 13/20 0.43
APEX1 P27695 1/20 0.37
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PGR P06401 2/20 0.34
MEN1 O00255 1/20 0.32
CRHBP P24387 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
CRHR2 Q13324 1/20 0.32
TLR9 Q9NR96 1/20 0.32
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17678560 0.97 PDK2 (0.42) PDK2APEX1CYP1A2CYP3A4CYP2D6
SCHEMBL17680057 0.95 PDK2 (0.41) PDK2APEX1ALDH1A1L3MBTL1KDM4E
SCHEMBL10018628 0.95 PDK2 (0.41) PDK2APEX1ALDH1A1L3MBTL1KDM4E
SCHEMBL17678567 0.95 PDK2 (0.41) PDK2APEX1ALDH1A1L3MBTL1KDM4E
SCHEMBL25750216 0.93 PDK2 (0.41) PDK2APEX1ALDH1A1L3MBTL1KDM4E
SCHEMBL17678563 0.92 PDK2 (0.39) PDK2APEX1PGR
SCHEMBL13658651 0.91 PDK2 (0.40) PDK2APEX1ALDH1A1L3MBTL1KDM4E
SCHEMBL28781068 0.91 PDK2 (0.40) PDK2APEX1ALDH1A1L3MBTL1KDM4E
SCHEMBL13622053 0.91 PDK2 (0.38) PDK2APEX1CYP2C19PGRELANE
SCHEMBL17678549 0.91 PDK2 (0.38) PDK2APEX1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101904028-A organic electroluminescent element IDEMITSU KOSAN CO 2010-12-01 CN disclosed
CN-101473464-A Organic electroluminescent element using heterocyclic aromatic amine derivative IDEMITSU KOSAN CO (JP) 2009-07-01 CN disclosed
US-7132572-B2 Fullerene compounds Chiang, Long Y. (US) 2006-11-07 US disclosed
US-20050191229-A1 Fullerene compounds CHIANG, LONG Y. 2005-09-01 US disclosed
WO-2004007426-A1 FULLERENE COMPOUNDS CHIANG LONG Y (US) 2004-01-22 WO disclosed