⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294654 | 1.00 | — | — | |
| SCHEMBL294653 | 1.00 | — | — | |
| SCHEMBL575832 | 0.72 | — | — | |
| SCHEMBL5803706 | 0.72 | — | — | |
| SCHEMBL6367267 | 0.71 | — | — | |
| SCHEMBL18639675 | 0.69 | — | — | |
| SCHEMBL13756675 | 0.69 | — | — | |
| SCHEMBL1744592 | 0.69 | — | — | |
| SCHEMBL2719219 | 0.69 | — | — | |
| SCHEMBL8181212 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028316-A1 | Biphenyl and Phenylpyridine Compounds | PFIZER INC. (US) | 2026-01-29 | — | — | US | disclosed |
| US-20250188030-A1 | Biphenyl and Phenylpyridine Compounds | PFIZER INC. (US) | 2025-06-12 | — | — | US | disclosed |
| US-20240317752-A1 | 6-SUBSTITUTED-9H-PURINE DERIVATIVES AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-09-26 | — | — | US | disclosed |
| CN-112437771-B | Bronchodilating heteroatom-linked amides | 阿凯德制药公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20240083877-A1 | NOVEL SCAFFOLD OF ADENYLYL CYCLASE INHIBITORS FOR CHRONIC PAIN AND OPIOID DEPENDENCE | PURDUE RESEARCH FOUNDATION (US) | 2024-03-14 | — | — | US | disclosed |
| US-11680054-B2 | Bronchodilating hetero-linked amides | ARCEDE PHARMA AB (SE) | 2023-06-20 | — | — | US | disclosed |
| US-11667623-B2 | Scaffold of adenylyl cyclase inhibitors for chronic pain and opioid dependence | PURDUE RESEARCH FOUNDATION (US) | 2023-06-06 | — | — | US | disclosed |
| WO-2022178256-A1 | 6-SUBSTITUTED-9H-PURINE DERIVATIVES AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-08-25 | — | — | WO | disclosed |
| EP-3466944-B1 | NICOTINYL ALCOHOL ETHER DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USES THEREOF | INST MATERIA MEDICA CAMS (CN) | 2022-06-15 | — | — | EP | disclosed |
| EP-3818055-B1 | NOVEL BRONCHODILATING HETERO-LINKED AMIDES | RESPIRATORIUS AB PUBL (SE) | 2022-02-16 | — | — | EP | disclosed |
| EP-0625156-A1 | [3H,7H]THIAZOLE[3,4-a]PYRIDINES HAVING ANTIASTHMATIC AND ANTIINFLAMNATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-11-23 | — | — | EP | disclosed |
| US-5336676-A | [3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory actions on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-08-09 | — | — | US | disclosed |
| WO-1993011133-A1 | [3H,7H]THIAZOLE[3,4-a]PYRIDINES HAVING ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-06-10 | — | — | WO | disclosed |
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |
| WO-1991018906-A1 | [3H,7H]THIAZOLO[3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-12-12 | — | — | WO | disclosed |
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0210571-A1 | Phosphonopyridines and their 1,4-dihydroderivatives | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1987-02-04 | — | — | EP | disclosed |
| US-3970622-A | Heat stabilizers for polyvinyl chloride (β-amino-β-arylacrylonitriles) | AMERICAN CYANAMID COMPANY (US) | 1976-07-20 | — | — | US | disclosed |
| US-3970644-A | Heat stabilizers for polyvinyl chloride (β-amino-β-arylacrylamides) | AMERICAN CYANAMID COMPANY (US) | 1976-07-20 | — | — | US | disclosed |