Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361168 | 0.92 | PDK2 (0.36) | PDK2BACE1HPGDLMNAALDH1A1 | |
| SCHEMBL20872220 | 0.92 | PDK2 (0.40) | PDK2APEX1PTPRCBACE1ALDH1A1 | |
| SCHEMBL18677952 | 0.92 | PDK2 (0.40) | PDK2APEX1PTPRCBACE1ALDH1A1 | |
| SCHEMBL5095683 | 0.92 | PDK2 (0.40) | PDK2APEX1PTPRCBACE1ALDH1A1 | |
| SCHEMBL30004248 | 0.85 | APEX1 (0.48) | PDK2APEX1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5329061 | 0.85 | APEX1 (0.48) | PDK2APEX1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16024284 | 0.85 | PDK2 (0.35) | PDK2HPGDLMNAALDH1A1MAPT | |
| SCHEMBL20147100 | 0.84 | PDK2 (0.33) | PDK2BACE1HPGDLMNAALDH1A1 | |
| SCHEMBL18415976 | 0.84 | APEX1 (0.47) | PDK2APEX1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4830511 | 0.83 | PDK2 (0.33) | PDK2BACE1HPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132572-B2 | Fullerene compounds | Chiang, Long Y. (US) | 2006-11-07 | — | — | US | disclosed |
| US-20050191229-A1 | Fullerene compounds | CHIANG, LONG Y. | 2005-09-01 | — | — | US | disclosed |
| WO-2004007426-A1 | FULLERENE COMPOUNDS | CHIANG LONG Y (US) | 2004-01-22 | — | — | WO | disclosed |