Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149333 | 0.89 | NR3C2 (0.60) | CYP3A4TDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL409370 | 0.86 | NR3C2 (0.57) | TDP1ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL6567347 | 0.86 | NR3C2 (0.57) | TDP1ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL16408145 | 0.84 | NR3C2 (0.56) | CYP3A4TDP1ALDH1A1MAPTL3MBTL1 | |
| Iodide SCHEMBL31634397 | 0.84 | NR3C2 (0.55) | TDP1ALDH1A1MAPTL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL27464725 | 0.84 | NR3C2 (0.55) | ALDH1A1MAPTL3MBTL1KDM4ECYP1A2 | |
| Bromide SCHEMBL6737911 | 0.84 | NR3C2 (0.55) | TDP1ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL7062571 | 0.83 | CYP3A4 (0.59) | CYP3A4TDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL18979892 | 0.82 | CYP3A4 (0.62) | CYP3A4TDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3368539 | 0.82 | NR3C2 (0.55) | CYP3A4TDP1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028999-B1 | PROCESS FOR THE PREPARATION OF ANTIOXIDANT AMIDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-03-23 | — | — | EP | claimed |
| EP-2923691-A1 | Method of suppressing background rise in color reagent solution, color reagent solution, reagent kit, and measuring apparatus | ARKRAY, Inc. (JP) | 2015-09-30 | — | — | EP | disclosed |
| CN-100534990-C | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-02 | — | — | CN | disclosed |
| US-7067549-B2 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2006-06-27 | — | — | US | disclosed |
| US-20050192292-A1 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2005-09-01 | — | — | US | disclosed |
| CN-1610678-A | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2005-04-27 | — | — | CN | disclosed |
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |
| EP-0581589-A2 | Phthalide compounds, and recording materials using the compounds | YAMAMOTO CHEMICALS, INC. (JP) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192292-A1 | Pyrrolidone carboxamides | NPY1R, NPY5R, NPY2R | CYP3A4 1975/4885TDP1 3359/4885ALDH1A1 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.