SCHEMBL58442

SCHEMBL58442

c1ccc(-c2cccc(-c3ccccc3)n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
RAB9A P51151 1/20 1.00
ASIC3 Q9UHC3 1/20 0.68
ALDH1A1 P00352 5/20 0.59
MAPT P10636 4/20 0.59
HPGD P15428 3/20 0.59
POLB P06746 1/20 0.59
HSD17B10 Q99714 1/20 0.59
ADORA2A P29274 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HSP90AA1 P07900 2/20 0.50
ADORA1 P30542 2/20 0.50
AURKA O14965 1/20 0.50
PRKACA P17612 1/20 0.50
KDM4E B2RXH2 2/20 0.48
LMNA P02545 2/20 0.48
TP53 P04637 1/20 0.48
ALPL P05186 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5945940 0.97 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
Bromide SCHEMBL10753629 0.97 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL4406097 0.97 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL16077969 0.97 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL18732402 0.94 MEN1 (0.89) MEN1KMT2ARAB9AASIC3ALDH1A1
Bromide SCHEMBL10757159 0.94 MEN1 (0.89) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL3631391 0.94 MEN1 (0.89) MEN1KMT2ARAB9AASIC3ALDH1A1
Hydrochloric Acid SCHEMBL4387943 0.92 KMT2A (0.84) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL23869334 0.89 MEN1 (0.80) MEN1KMT2ARAB9AASIC3ALDH1A1
Boric Acid SCHEMBL28377147 0.89 MEN1 (0.80) MEN1KMT2ARAB9AASIC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 846 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US claimed
CN-118852060-A Preparation method of glycidyl ether without organic chloride 浙江大学衢州研究院 2024-10-29 CN claimed
CN-118345390-A Method for preparing carbonyl compound by electrocatalytic oxidation of benzyl C-H bond by pyridine nitrogen oxide 浙江大学 2024-07-16 CN claimed
CN-118307410-A Preparation method of chiral secondary alcohol compound 武汉大学 2024-07-09 CN claimed
CN-118290070-A Modified yarn-throwing ceramic fiber asphalt mixture, and preparation method and application thereof 山东省大通建设集团有限公司 2024-07-05 CN claimed
CN-114478492-B From CF 3 SO 2 Na-mediated method for cross dehydrogenation and coupling of photocatalytic heteroarene and aliphatic compound bond 南京工业大学 2024-04-09 CN claimed
CN-114206886-B Gold (III) compound, method for preparing the same, and organic light emitting device using the same 广东聚华印刷显示技术有限公司 2024-02-27 CN claimed
CN-117534688-A Perylene diimide-gold (III) luminophore, luminescence sensing film, fluorescence sensor and application 陕西师范大学 2024-02-09 CN claimed
CN-116425791-A Photochromic germanium-doped cyclopentadiene condensed diaryl ethylene and preparation thereof 香港大学 2023-07-14 CN claimed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998002405-A9 PROCESS FOR THE SEPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1, 2-DIOLS FROM CATALYSTS 1998-06-04 WO claimed
WO-1998002404-A1 PROCESS FOR THE PREPARATION OF 2-ALKENE-1,4-DIOLS AND 3-ALKENE-1,2-DIOLS FROM η,δ-EPOXYALKENES EASTMAN CHEMICAL COMPANY (US) 1998-01-22 WO claimed
EP-0451556-B1 Stabilised polyaryletherketone - moulding compounds BASF AG (DE) 1996-01-10 EP claimed
US-5334642-A Includes organic compound which has a base constant within the range 2 to 12 and boiling point higher than 300 degrees BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
US-5294581-A Polypropylene, polybutylene SHELL OIL COMPANY (US) 1994-03-15 US claimed
US-5208278-A STABILIZED POLYARYL ETHER KETONE MOLDING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1993-05-04 US claimed
US-5118767-A Catalysis using a coordination catalyst of a magnesium alkoxide or aryl oxide and a tetravalent titanium halide, an organoaluminum compound and a selectivity control agent SHELL OIL COMPANY (US) 1992-06-02 US claimed
EP-0451556-A2 Stabilised polyaryletherketone - moulding compounds BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
US-4830846-A SALT FORMATION AND NEUTRALIZATION THE DOW CHEMICAL COMPANY (US) 1989-05-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof AGL, GMNN, GAK MEN1 1502/4885KMT2A 2472/4885RAB9A 2008/4885
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK MEN1 1502/4885KMT2A 2472/4885RAB9A 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.