SCHEMBL5844702

SCHEMBL5844702

O=C(O)c1ccc(Oc2ccccc2C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.63
KDM4E B2RXH2 4/20 0.51
MAPT P10636 4/20 0.49
LMNA P02545 3/20 0.49
HSD17B10 Q99714 2/20 0.49
HPGD P15428 2/20 0.49
CYP3A4 P08684 1/20 0.49
RECQL P46063 1/20 0.49
CYP2C8 P10632 1/20 0.47
CYP2C9 P11712 1/20 0.47
SRC P12931 1/20 0.46
TGFBR1 P36897 1/20 0.46
AKR1C3 P42330 1/20 0.46
ELANE P08246 1/20 0.46
SRD5A2 P31213 1/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
KMT2A Q03164 1/20 0.44
KEAP1 Q14145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10937410 0.84 ELANE (0.53) KDM4EMAPTLMNAHSD17B10HPGD
SCHEMBL9282306 0.82 ELANE (0.61) KDM4EMAPTLMNAHSD17B10HPGD
SCHEMBL14213146 0.82 TTR (0.76) TTRKDM4EMAPTLMNAHSD17B10
SCHEMBL31465303 0.82 TTR (0.76) TTRKDM4EMAPTLMNAHSD17B10
SCHEMBL2879416 0.79 KMT2A (0.48) TTRKDM4EMAPTLMNAHSD17B10
SCHEMBL28331260 0.78 SRD5A2 (0.64) TTRKDM4EMAPTCYP2C8CYP2C9
SCHEMBL2706776 0.78 TTR (1.00) TTRKDM4EMAPTAKR1C3SRD5A2
SCHEMBL10660681 0.77 KDM4E (0.70) TTRKDM4EMAPTLMNAHSD17B10
SCHEMBL7536365 0.77 TTR (0.63) TTRKDM4EMAPTLMNAHPGD
SCHEMBL27695682 0.76 MAPT (0.52) KDM4EMAPTLMNAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125442-B2 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-24 US disclosed
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same CDK4, CDKL4, UGT1A4 TTR 1591/4885KDM4E 276/4885MAPT 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.