Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583490 | 0.86 | TSHR (0.59) | TDP1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL13589550 | 0.81 | TDP1 (0.47) | TDP1NPC1THRBRAB9ASMN1; SMN2 | |
| SCHEMBL1940677 | 0.80 | — | — | |
| SCHEMBL12703364 | 0.79 | SMN1; SMN2 (0.54) | TDP1NPC1THRBRAB9ASMN1; SMN2 | |
| SCHEMBL27726587 | 0.79 | TDP1 (0.46) | TDP1NPC1THRBRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11161525 | 0.78 | — | — | |
| Methoxymethane SCHEMBL11416469 | 0.78 | HPGD (0.47) | TDP1NPC1THRBRAB9ASMN1; SMN2 | |
| SCHEMBL20761935 | 0.77 | SMN1; SMN2 (0.45) | TDP1NPC1THRBRAB9ASMN1; SMN2 | |
| SCHEMBL28065431 | 0.77 | KDM4E (0.44) | TDP1NPC1THRBRAB9ASMN1; SMN2 | |
| SCHEMBL150973 | 0.77 | TDP1 (0.45) | TDP1NPC1THRBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168957-B1 | Alkyl-substituted tetrahydropyranes as aromatic materials | SYMRISE AG (DE) | 2012-02-15 | — | — | EP | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |