Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377231 | 0.83 | PPARG (0.46) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL5845568 | 0.81 | PPARG (0.51) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL5846121 | 0.81 | PPARG (0.48) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL5845540 | 0.80 | PPARD (0.45) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL5846647 | 0.79 | PPARD (0.52) | KDM4EALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL5845397 | 0.78 | PPARD (0.44) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL376647 | 0.77 | PPARG (0.42) | KDM4EALDH1A1LMNAL3MBTL1HPGD | |
| SCHEMBL376646 | 0.77 | PPARG (0.42) | KDM4EALDH1A1LMNAL3MBTL1HPGD | |
| SCHEMBL16399227 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 | |
| SCHEMBL376642 | 0.73 | PPARG (0.45) | KDM4EALDH1A1LMNAL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078422-B2 | Activator for peroxisome proliferator-activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2006-07-18 | — | — | US | disclosed |
| US-20040152744-A1 | Activator for peroxisome proliferator- activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1371650-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152744-A1 | Activator for peroxisome proliferator- activated receptor | PPARA, PPARG, PPARD | KDM4E 3765/4885ALDH1A1 768/4885LMNA 1937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.