Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765909 | 0.94 | PPARD (0.46) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL5846793 | 0.90 | PPARD (0.47) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL376890 | 0.89 | PPARG (0.49) | PPARDPPARGPPARATP53SMN1; SMN2 | |
| SCHEMBL5845540 | 0.87 | PPARD (0.45) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL5846365 | 0.84 | PPARD (0.46) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL24658486 | 0.83 | PPARD (0.45) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL30003787 | 0.83 | PPARD (0.45) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL7101627 | 0.83 | PPARG (0.51) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL30003783 | 0.83 | PPARD (0.45) | PPARDPPARGPPARANR1H4TP53 | |
| SCHEMBL5845148 | 0.83 | PPARD (0.45) | PPARDPPARGPPARANR1H4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014652-B1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-8404726-B2 | Activating agent for peroxisome proliferator activated receptor δ | NIPPON CHEMIPHAR CO. LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-8404726-B2 | Activating agent for peroxisome proliferator activated receptor δ | NIPPON CHEMIPHAR CO. LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO. LTD | 2009-12-03 | — | — | US | disclosed |
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO. LTD | 2009-12-03 | — | — | US | disclosed |
| EP-2014652-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-7078422-B2 | Activator for peroxisome proliferator-activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2006-07-18 | — | — | US | disclosed |
| US-20040152744-A1 | Activator for peroxisome proliferator- activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1371650-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | PPARD 3/4885PPARG 2/4885PPARA 1/4885 |
| US-20040152744-A1 | Activator for peroxisome proliferator- activated receptor | PPARA, PPARG, PPARD | PPARD 3/4885PPARG 2/4885PPARA 1/4885 |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | PPARD 3/4885PPARG 2/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.